Growing up with animals can make you more flexible as an adult

Rural education with a lot of contact with animals has ensured that the immune system and mental resistance to stress are more effective than a city free of pets.
Cows in a field with children
Growth in a rural environment around animals can mean mental improvement.
This was the conclusion of a new research led by the University of Ulm in Germany and now published in Keto Blaze PNAS.

This study is by no means the first to suggest that urban growth that lacks microbial diversity can undermine physical health.

In this sense, it is added to the growing evidence in support of the theories that have evolved from the “hygiene hypothesis”.

But the study is the first to suggest that an increased risk of mental disorders, possibly due to an “exaggerated immune response,” may be another unexpected result of growth in an environment less likely to interact with a variety of microbes.

Study co-author Christopher A. Laurie, professor of integrative physiology at the University of Colorado at Boulder, said: “It has been very well documented,” that exposure to pets and rural environments during development is useful to reduce the risk of asthma and allergies later in life. ”

However, he adds, his study also “advances the conversation by showing for the first time in humans that these same estimates are probably important for mental health.”

Loss of contact with advanced microbes
Human existence has become increasingly civilized. In 1950, only a third of the world’s population lived in cities. By 2014, this figure has increased to 54% and is expected to increase to 66% by 2050.

The idea of ​​greater urbanization and changes in lifestyle that accompany it may increase the risk of certain diseases due to the reduced interaction with a variety of microbes derived from the hygiene hypothesis.

The theory is rooted in research 30 years ago that suggests that the low infection rate among young children was the cause of high rates of asthma and allergic diseases in the 20th century.

However, it has become clear that the interaction with microbes exceeds this original range, and has even suggested that the term hygiene hypothesis is an inappropriate name and should be abandoned.

In his article, lead author Stephan or Rieber, a professor of Molecular Molecular Psychology at the University of Ulm, and his team used the term “old friends” to refer to the microbes that evolved with humans.

Researchers find a “mental change” of courage

When we see danger, we interact. Whether we choose to play, hide or face our threat face to face, our “immediate” decision is the result of a complex brain mechanism that integrates visual data and stimulates the appropriate response. How does this happen? Explain a new study
Brain contact illustration
Soon we can “activate” the key Rapid Results Keto of courage in the brain, helping people overcome the symptoms of PTSD.
In the animal kingdom, vision is vital for survival. This important meaning teaches the brain about predators and other threats, and, in turn, the brain generates an appropriate reaction: courage or fear, fight or escape.

But how is this process carried out? How can animals, including humans, integrate visual information with the appropriate brain circuits that first control our emotional state and then our behavior and our actions?

A new search brings us an answer. Scientists led by Andrew Huberman, associate professor of neuroscience and ophthalmology at the Stanford University School of Medicine, discovered that brain circuits are “responsible” for the decision to fight or escape danger.

Although the study was conducted in mice, the results are related to humans. In fact, the results have significant implications for understanding and managing post-traumatic stress disorder (PTSD), addiction and phobias.

Lindsey Sally is the first author of the article, which has now been published in the journal Nature.

Brain circuit of fear
To test the rodent’s response to the threat, Sally and her team simulated the prey approach and used a c-Fos to track neural activity in mice.

The researchers found an increase in the activity of the neurons that were assembled in a structure called thrombus of the ventral midline (VMT).
Using brain maps, scientists can learn sensory information and what information comes out of vMT.

The researchers revealed that the VMT receives information from a wide range of areas of the brain that have to do with internal situations, such as the state of fear, but the information is very selective to send, to only two main areas: the basal lateral amygdala and the medial prefrontal cortex.

The amygdala treats fear, aggression and other emotions, while the prefrontal cortex uses its executive function to modify emotional responses. The region is also deeply concerned.

The additional analysis showed more light on the path of the brain circuit involved in the response of rodents to the ominous animal.

Apparently, the nervous system starts from the “xiphoid nucleus” (a group of neurons in the vMT) and continues towards the basolateral lateral amygdala.

Another path follows a similar course, this time from the so-called nunas reuniens, another group of neurons built around the xiphoid nucleus that leads to the cortex of the frontal lobe.

Seasonal emotional upheaval: Why women with brown eyes are at risk

Two new studies suggest that sex and eye color affect the risk of seasonal affective disorder. The researchers also provided some interesting explanations on why.
Establish a structure
NEW YORK (Reuters Health) – Women with brown eyes may face seasonal depression, a new study shows.
Seasonal affective disorder (SAD), a keto lux psychological state, is often characterized by feelings of desperation and extreme sadness that occur during the fall and winter.

A form of depression, it is estimated that SAD affects 5 percent of the US population. UU Of these, it is believed that women are at greater risk.

In fact, it is believed that 4 out of 5 people living with the condition are women.

Previously, the researchers found that the strong prevalence of SAD among women is independent of social factors or lifestyle, suggesting that there are biological biological differences that are responsible for preparation.

Recent research confirms that women are more prone to the condition, but add an interesting element to the mix: the color of the eyes.

In addition, the new studies provide new and disturbing explanations about why sex and eye color can affect the risk of SAD.

The Group presented the results at the annual conference of the British Psychological Society in Nottingham, United Kingdom, by Lance Workman, a professor at the University of South Wales, and also in the United Kingdom.

Why the blue eye keeps the penumbra
The first study that will be presented by Professor Trabajador – entitled “Blue eyes keeps the penumbra: the relationship between the SAD emotions, inherent, and the color of the eyes” – that interviewed 175 students of the University of South Wales and the American Girne University in the north of Cyprus.

The results of the questionnaires showed that participants with brown eyes were significantly more likely to have mood swings than those with blue eyes.

Professor Wurkman has an interesting explanation for this. “We know that light entering the brain causes lower levels of melatonin,” he says.

“As the blue eye allows more light in the brain, this can lead to a greater reduction in melatonin during the day and that is why people with lighter eyes have less chance of SAD.”

Professor Lance Workman
“Blue-eyed individuals appear to have some degree of flexibility with respect to SAD,” the authors explain.

“This,” they add, “may be implied that the blue eye mutation has been selected as a precautionary measure, while the migration of the SAD subgroups of people to the northern latitudes.”

What is basophilia? Causes and symptoms

Basophilia refers to the presence of many basal cells in a person’s blood. Basophils are a type of white blood cell.
Basophilia is not a condition in keto x factor itself, but it can be an important sign of other underlying medical problems.

What is basophilia?
White blood cells
Bad urine usually indicates another underlying medical condition.
In healthy individuals, basal cells are responsible for the minimum number of cells in the body. However, people suffering from lack of sleep contain an abnormally large amount of basal cells.

Basophils are a type of white blood cell produced in the bone marrow. White blood cells help the body resist infection.

A high level of white blood cells can indicate an immune response in the body, which protects the body from infections and other problems. However, when a person is sick, the increase in white blood cells may be due to more serious causes.

Basophilia is rarely found independently and often indicates another condition.

Causes and risk factors
The most common causes of basophilia include:

Infection
Sensitivity
Disorders and diseases characterized by chronic inflammation
Reproductive disorders
Infection
The infection often causes an inflammatory response in the body, which can make a person more susceptible to poor digestion.

However, the appearance of the norm rarely occurs as a result of a serious infection or illness. Some diseases, including chickenpox and tuberculosis, can make a person more likely to develop poorly.

Sensitivity
Allergies and allergies to food and medicine can cause a feeling of ascites. The sensitivity or severity of the response may be associated with the severity of the liver condition.

Chronic inflamation
Many disorders and diseases are directly related to chronic inflammation. A person with inflammation that is characterized by inflammation may be more likely to develop cancer.

The cases that cause chronic inflammation include:

Rheumatoid arthritis
Inflammation of the bowel syndrome (IBD)
Psoriasis
Hashimoto’s thyroiditis

What to do when you can not stop sneezing

Sneezing is a reaction to irritants and a way for the nose to eliminate germs. Almost any particle can irritate the nose and cause sneezing.
Common irritants include:

Virus or bacteria
Dust
Vaccine
Go to
All these particles can cause sneezing. activated xtnd Sneezing is an interaction that can be partially controlled by irritants. Therefore, it is possible to delay or even stop sneezing before it happens.

12 way to stop sneezing
It is possible to delay or stop sneezing normally when:

1. Allergy treatment
A man is about to sneeze
Irritants, such as pollen and dust, aggravate the nose and cause sneezing.
Allergy treatment is a good way to prevent sneezing. Sneezing often occurs in groups of two to three.

However, for the treatment of allergies, the person must first determine what triggers the allergic reaction. Once identified, a person can avoid allergens and avoid sneezing due to allergies.

There may be times when allergens can not be avoided.

In these cases, people can control their interactions with allergens by using over-the-counter medications that can help with allergies.

Popular types include:

Antihistamines or pills
Nasal sprays of glucocorticosteroids
Some people with more severe reactions may need medical injections or sensitizers to prevent or minimize the effects

2. Learn the triggers
Different things can make someone sneeze. It can be easy to identify and avoid some of these stimuli. Learning what causes sneezing can help people avoid it.

The operators include:

Go to
Dust
Spices, like peppers
Bright lights
The food is spicy
Template
Vaccine
Cold virus
Fragrance
Bread flour
3. Treatment of sneezing
Sneezing when looking at a bright light is called optical sneezing. This condition affects about a third of people worldwide, who are activated to start sneezing out on a bright day.

People with photosynthesis usually have a family history of this condition. They can avoid sneezing by not looking directly at bright lights and wearing sunglasses on sunny days.

4. Avoid large meals
Some people sneeze after eating and feel particularly full. This interaction can be prevented by taking smaller portions and taking smaller bites. This phenomenon is not well understood.

5. Say something strange
People say that saying a funny or strange word before sneezing can prevent sneezing from happening. They are pure stories.

The idea is that the verbal act of something interesting or unusual distracts the brain to avoid sneezing. There is no investigation to support these accusations.

6. Tickle the lid of the mouth
A person can stifle sneezing by stimulating the palate with the tongue. Doing this for several seconds before sneezing can help prevent it.

Invites the endocrine community to an integrative approach to improve diabetes care

To provide comprehensive care to people with diabetes who may be vulnerable to related medical complications, the needs of the health care system in the United States to continue building multidisciplinary team care models, according to the new recommendations of the Society of Endocrinology.

The analysis published Super Keto challenges and opportunities of the Endocrinology Society created by the application of the Soft Care Act (ACA) on the Internet today in the Journal of Clinical Endocrinology and Metabolism.

The policy recommendations were developed by medical experts on diabetes as a result of the Society’s policy summit in September 2014 on diabetes and the implementation of ACA. The field of endocrinology involves physicians (MD) who are highly specialized in the management of diabetes, as well as scientists who seek diabetes.

An estimated 29 million Americans have diabetes, according to a report of endocrine facts and figures in society. The condition occurs when the body’s ability to process sugar is affected. In 2012, treatment for diabetes cost the US health care system. UU $ 245 billion, a figure that is expected to double by 2021.

The number of people with diabetes is likely to increase as the number of people who receive health insurance coverage increases through ACA. One study found a 23 percent increase in Medicaid patients who have been diagnosed with diabetes in states that have adopted the expansion of ACA Medicaid, compared with a 0.4 percent increase in the US. , that has not been diagnosed. Approximately one in four Americans with diabetes is not diagnosed, so expanding access to care is likely to lead to early diagnosis and treatment.

People with diabetes are at an increased risk of developing other conditions, such as eye problems and foot complications, which may require amputation, nerve pain, diabetes and kidney problems. As a result, they often have to see a variety of medical specialists, such as kidney disease doctors, podiatrists, or ophthalmologists who can become part of the “patient care team.”

“The main challenge in the care of patients with diabetes is how we can convert various disciplines care teams to provide optimal care,” said the lead author in the White Paper, the world’s endocrine Alphen C Bowers, MD, University of Vanderbilt Medical Center in Nashville, Tennessee. “Coordinated care is necessary to ensure the best possible outcomes for people with diabetes.Effective team-based approach and a comprehensive continuum of care must be provided in a timely manner, without duplicating tests or services.”

Texas lacks insurance for a clear understanding of its health insurance plans

The main confusion for Texas that bought individual health insurance.
It was unlikely that Texans who bought their health insurance understood the basic conditions and how to use their plans compared to those who had health insurance, medical care or keto fire diet medical care. This is one of the findings of a new report issued by the Baker Institute for Public Policy of the Rice Foundation and the Episcopal Health Foundation (EHF).

The report found that the percentage of Texas that purchased individual health insurance plans increased by 78 percent (to 18 percent from 10 percent) from 2013 to 2015. The increase includes 1.3 million Texans who bought Affordable health care market plans. However, the researchers discovered that Texas, which purchased individual plans, was much less likely to understand the basic terms of health insurance, such as “premium,” “reimbursement,” and “deductible.”

For example, 25 percent of Texans with health insurance sponsored by staff said they lacked confidence in understanding the term “maximum out-of-pocket costs.” But more than 42 percent of Texas residents who bought their own health insurance plans said they did not understand the same term.

“It’s ironic that people with individual health insurance plans are less likely to understand basic conditions, but they have the greatest need to understand them,” said Elena Marks, president and CEO of EHF and a non-resident health policy partner. Baker. Institute. “This group must choose from a variety of health insurance options and pay much more for their insurance.” They need to understand what they are buying. ”

The report found that Texas residents who purchased their health insurance had more difficulty understanding how to use their health plans. More than half (51%) said they lacked the confidence to understand how much it would cost to go to caregivers outside of their plan’s network. Almost half (46%) said they did not understand what preventive services they were, many of which covered health plans at no additional cost.

The researchers found that Texas with health insurance, medical care and military-sponsored personnel had difficulty understanding the basic terms of health insurance and how to use their plans. However, their lack of confidence was about one third lower than that of Texans who purchased individual health insurance.

Middle-aged adults with hearing loss have significantly higher health care costs

In a study published online by the Department of Ear, Nose, and Throat Surgery and JAMA Neck Surgery, Annie N. Simpson, of the University of South Carolina Medical, Charleston, and colleagues, compared the costs of medical care with a identical group of particularly faithful advanced keto individuals. With and without diagnosis of hearing loss.

Age-related hearing impairment affects more than 60 percent of adults in the United States over the age of 70, starting gradually, with three times more than 50 to 60 years. However, the association between hearing loss in middle-aged people (55 to 64 years old) and the use of medical care was not studied. In this study, the researchers included data on particularly insured individuals aged 55 to 64 years with diagnostic coding for hearing loss and their compliance with the comparison group. The collection of medical care accounts for a maximum of 18 months of follow-up after the baseline by the patient to calculate total payments for inpatient services, outpatient services and prescription medications, and the cost of hearing services. A total of 561,764 people were included in the study.

The researchers found that people who have a diagnosis of hearing loss have received payments for superior medical care by 33 percent (average, $ 14,165) over the 1.5-year period compared to patients who do not suffer from loss of Hearing (average, $ 10,629). “This result indicates that the negative effects associated with health caused by hearing loss, a condition that many see as a result, can not prevent aging, which may appear earlier than is generally recognized and may affect the Use of healthcare throughout the continuum of the care chain Identify the key factors that lead to observed differences in costs, as well as to determine the extent of early use and success of aids and other hearing loss interventions for Adjust cost differences, however, our study suggests that hearing loss is expensive, even in middle-aged hearing individuals, and that they are present in a large number of Adults Who can be prevented through a successful early intervention of hearing impairments and a reduced quality of life “.

Donations from members of the death by overdose can alleviate the crisis

About 20 people die in need of a transplant each day while waiting for a game. We need better solutions, but organ transplantation is fraught with risks. Could donations from those who died from overdoses provide a partial solution, despite concerns about potential risks?
A doctor holds a container of human organs to cultivate
Are members of donors who advanced keto have used an overdose safer than previously thought?
According to the US Department of Health and Human Services. UU., More than 116,000 US citizens have registered for transplants since August 2017.

They say that the waiting list lengthens every year, but the amount of organ donations increases at a very slow pace to meet the growing need.

Dr. Christine M. Durand – of the Johns Hopkins University School of Medicine in Baltimore, MD – recently conducted a study focused on the least intuitive way to address this problem: improving the voluntary contributions of members of the overdose deaths.

Often, these organs, especially the liver and kidneys, are eliminated for fear of putting the future at risk of chronic diseases such as HIV and hepatitis.

However, Dr. Durand’s research suggests that potential recipients face a greater health risk while suspended.

According to Dr. Durand and colleagues, from 2000 to present, the number of devices received from donors who have died of overdose 24 times higher. Why do not we often use them to supplement the national shortage of donated members?

The new study, published in the Annals of Internal Medicine, discusses the pros and cons of better organ donation obtained from people who died from an overdose.

Beneficiaries with a lower risk than the dreaded
The team worked with its origin through the scientific record of Almzruaan recipients to build a medical file of organ donors who died of an overdose and check survival and other health outcomes for people who received organs from these donor data rates.

Therefore, they analyzed data from 138,565 dementia donors, in addition to 337,934 recipients, available between 2000 and 2017.
First, Dr. Durand and his colleagues observed that the number of members of donations of people who died of overdose has increased dramatically in the past 17 years, from approximately 1 percent in 2000 to more than 13 percent in 2017

But more importantly, they found that the health outcomes of the recipients of organ transplants that members of these donors accepted were, in general, worse than those who received the members of the donors are healthy agriculture.

In fact, the results of the previous group of beneficiaries were sometimes better than the patients who received transplants from other donors.

Surprisingly, opioids may increase the risk of chronic pain

After surgery, opioids, such as morphine, are routinely used to control pain. However, according to a new study, medications can actually increase the likelihood of experiencing chronic pain.
Opioid drugs and the word
New study reveals a new concern Shakra Keto about the use of opioids.
Opioids are good news. The “opium epidemic” in the United States destroys life from coast to coast.

More than 100 people die from an opiate overdose every day in the United States.

Despite the horrors of addiction, one aspect of opioid use that is rarely questioned is how effective they are in achieving their primary function: to soothe pain.

After being used in one form or another for thousands of years, opioids multiply the pain in submission, making the patient feel more comfortable. The latest study, conducted at the University of Colorado at Boulder, made this firmly on its head.

“There is another dark side to opiates that many people doubt,” says lead researcher Professor Linda Watkins of the Department of Psychology and Neurology.

In this case, not the additional problems mentioned by Professor Watkins. Ironically, opioids can prolong pain after surgery. The results were recently published in Anesthesia and Analgesia.

Examine the pain of stock exchanges and opiates
For the study, Professor Watkins and his colleague Peter Gray of the MD Anderson Cancer Center in Houston, Texas, performed a laparotomy on male rats. This procedure involves incision through the abdominal wall to reach the inside of the abdomen, and this is done to tens of thousands of American people each year.

“Opioids are really effective in relieving acute pain, but little research is done to see what they do in weeks or months after they are removed.”

Peter Grace
After surgery, one group of mice received the equivalent of a moderate dose of morphine for the next seven days, while another group received morphine for 8 days and the dose was excluded on day 10.

Another group of morphine was administered for 10 days, and then the treatment stopped abruptly. The last group received injections of saline instead of morphine as the control group.

In another trial, a group of mice received a cycle of morphine for 7 days that ended one week before surgery.

Before the morphine system was started, once finished, the sensitivity of the rats to the touch was measured, as was the activity of the genes related to spinal cord inflammation.

Compared to mice that received saline, those who received postoperative pain with morphine were tolerated for more than 3 additional weeks. Also, the longer the morphine is delivered, the worse the pain in the mice.

The study also found that the decrease in the dose of morphine was not different. As Grace explains: “This tells us that this is not a phenomenon related to the withdrawal of opium, which we know can cause pain.

How can morphine relieve pain after surgery?
The next question, of course, is what drives this obvious effect. Professor Watkins calls it a “one hit” result in glial cells.

In the brain, glial cells are more numerous than neurons. It protects and supports neurons, and as part of their protective function, directs the immune response to the brain, including inflammation.

The first “heartbeat” occurs when surgery activates future 4 as (TLR4) in the glial cells. Professor Watkins describes this as “not me, it’s not true, it’s not right”. Receptors Help regulate the inflammatory response. This first blow drives them to work when the second blow occurs.